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Scientists think the barrier degrades over time

doi:10.3233/CH-2012-1544

Routine monitoring is appropriate for: Mild redness or swelling at the injection site that resolves within a few days Slight itching without other symptoms Small, painless nodules at injection sites that gradually diminish Keep a record of when reactions occur, their appearance, duration, and any accompanying symptoms

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Moreover, the deposit of A in the vascular system may lead to the development of cerebral amyloid angiopathy, which is frequently observed in AD and involves cerebrovascular pathology (Glenner and Wong, 1984)